New York City hedge fund magnate Robert Miller (Richard Gere) manages a fund with his daughter Brooke (Brit Marling) and is about to sell it for a handsome profit.

In Manhattan during the early 1990s, Frank Pierce is a burned-out hospital paramedic who works the graveyard shift in a two-man ambulance team with various partners.

A hitchhiking teenage runaway, Sheila, is picked up on Interstate 605 in the Greater Los Angeles Area by a woman with a toddler.

A vending machine robbery by small-time thief and drug addict Bobbie goes badly awry, and his friends contact street-wise thief and part-time druggie Mel to patch him up.

A young boy dies from a stray bullet during a shootout between a cop and mob family member who had previously been supiciously given probabtion, only to break its terms.

In New York City, Helen returns to the apartment she shares with her boyfriend, Marco, after enduring an unhygienic and inept abortion.

In 1976, in South Africa during apartheid, Ben Du Toit (Donald Sutherland) is a South African school teacher at a school for whites only.

Trapped in his drug-dependent mother's apartment, 16-year-old Finn Earl (Anton Yelchin) wants nothing more than to escape New York City.

John Skillpa (Cillian Murphy), a quiet bank clerk living alone in tiny Peacock, Nebraska, prefers to live an invisible life in order to hide his secret: He has dissociative identity disorder, the implied result of childhood trauma inflicted by his abusive mother.

Avery "Ave" Ludlow, a storekeeper, has a dog named Red, a gift for his 50th birthday from his late wife, Mary.

Edmond Burke is a middle-aged New York City businessman who visits a tarot fortune teller on the way home.

Note: The story is explained here in its chronological order, rather than as it is presented in the film.

Roseanne (Monica Keena) is outwardly a perfect and popular teen, who suffers from a dysfunctional home life.

Freddy Gale (Nicholson) has been tormented for the five years following the death of his daughter Emily.

The story revolves around a perpetual loser and slacker named Richter Boudreau (Eric Stoltz).

Charlie, a young Italian-American man in New York's Little Italy, is hampered by his feeling of responsibility towards his reckless younger friend Johnny Boy, a small-time gambler and ne'er-do-well who refuses to work and owes money to many loan sharks.

In New York City, a middle-aged black insurance salesman named Doyle Gipson is a recovering alcoholic who is attending Alcoholics Anonymous meetings to stay sober.

Victor "Vic" Rosa (Leguizamo) is a drug dealer in New York City who sells a specific brand of heroin called "Empire".

Shotgun Stories is a 2007 drama film about a feud between two sets of half-brothers following the death of their father in rural Arkansas.

Aging private detective Harry Ross, an ex-cop, is working on a case to return 17-year-old runaway Mel Ames to her parents' home.